Zoladex LA 10.8mg Injection is used for the treatment of prostate cancer in men. Zoladex LA 10.8mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Hot flashes are a very common side effect of this medicine. It may also cause injection site reactions such as pain, swelling, and redness. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine.